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Table 1 IC 50 values of the different fractions and alkaloids from BFU against tumor cell lines

From: Evaluation of antitumor property of extracts and steroidal alkaloids from the cultivated Bulbus Fritillariae ussuriensis and preliminary investigation of its mechanism of action

Fractions/compounds

IC50(μg/ml)

LLC

A2780

HepG2

A549

HE

660.11 ± 16.71

246.97 ± 18.78

288.95 ± 17.84

294.96 ± 24.46

WE

614.74 ± 19.55

208.38 ± 23.57

279.09 ± 13.06

461.26 ± 28.38

CE

97.55 ± 4.02

88.50 ± 5.26

128.26 ± 12.55

172.59 ± 6.59

TAFU

39.37 ± 2.36

27.65 ± 1.84

51.10 ± 2.84

58.60 ± 3.99

Verticine

16.53 ± 0.82

48.41 ± 2.58

53.38 ± 3.16

97.58 ± 3.72

Vericinone

3.03 ± 0.32

17.03 ± 0.89

14.64 ± 0.65

47.39 ± 1.90

Imperialine

66.26 ± 3.46

39.18 ± 2.21

84.26 ± 4.46

117.84 ± 6.29

Peimisine

20.75 ± 1.44

17.43 ± 0.80

92.07 ± 4.89

36.11 ± 1.70

  1. The reported values are the means ± S.E.M. (n = 3).