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Table 2 Effect of SA on IL-1 Levels in Intestinal Tissue in an in-vivo

From: Anti-Inflammatory properties of Salograviolide A purified from Lebanese plant Centaurea ainetensis

Treatment Levels of IL-1 (ng/ml) in Colonic Tissues Removed 6 h After Treatment Levels of IL-1 (ng/ml) in Colonic Tissues Removed 24 h After Treatment
Rats treated with SA alone
(control, n = 3)
8.9 ± 1.9 12.1 ± 0.3
Rats treated with iodoacetoamide (representing inflamed tissue, n = 3) 27.3a± 3.0 18.6 ± 0.6
Rats treated with SA prior to iodoacetoamide treatment
(represents recovered tissue, n = 3)
16.6b± 0.2 11.4 ± 1.4
  1. a P < 0.005, a P value represents the comparison of IL-1 levels in iodoacetoamide treated tissue as compared to untreated control. Data are means ± SE of 3 separate experiments.
  2. b P < 0.05, b P value represents the comparison of SA pretreatment on IL-1 levels in iodoacetoamide treated rats as compared to iodoacetoamide treated rats. Data are means ± SE of 3 separate experiments.