Anti-Inflammatory properties of Salograviolide A purified from Lebanese plant Centaurea ainetensis

Table 2 Effect of SA on IL-1 Levels in Intestinal Tissue in an in-vivo

Treatment	Levels of IL-1 (ng/ml) in Colonic Tissues Removed 6 h After Treatment	Levels of IL-1 (ng/ml) in Colonic Tissues Removed 24 h After Treatment
Rats treated with SA alone (control, n = 3)	8.9 ± 1.9	12.1 ± 0.3
Rats treated with iodoacetoamide (representing inflamed tissue, n = 3)	27.3^a± 3.0	18.6 ± 0.6
Rats treated with SA prior to iodoacetoamide treatment (represents recovered tissue, n = 3)	16.6^b± 0.2	11.4 ± 1.4

^a P < 0.005, ^a P value represents the comparison of IL-1 levels in iodoacetoamide treated tissue as compared to untreated control. Data are means ± SE of 3 separate experiments.
^b P < 0.05, ^b P value represents the comparison of SA pretreatment on IL-1 levels in iodoacetoamide treated rats as compared to iodoacetoamide treated rats. Data are means ± SE of 3 separate experiments.

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