Effect of Pt in HUVEC viability evaluated by MTT assay. After incubation with 8 μM Pt, the percentage of cell viability was 63.33% ± 8.12% as evaluated by MTT assay. Results are expressed as percentage of control cells. Bars represent mean ± SD. Assays were repeated five times and performed in triplicate. Statistical significance between various groups was evaluated by one-way analysis of variance (ANOVA test) followed by the Tukey-Kramer multiple comparisons test. *p < 0.001 vs. Control; black diamond: p < 0.01 of 8 μM vs. 32 μM; black spade: p < 0.01 of 8 μM vs. 64 μM; §p < 0.001 of 8 μM vs. 128 μM; #p < 0.001 of 16 μM vs. 128 μM; black club: p < 0.05 of 32 μM vs. 128 μM.