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Table 1 The effect of PK and Omez on the levels of TBARS, protein carbonyls, non-protein thiol, and mucin in the ulcerated gastric tissue of micea on day one of ulceration

From: Healing Potential of Picrorhiza kurroa (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration.

Parameters Group I mice normal control Group II 1st day ulcerated control Group III PK-treated Group IV Omez-treated
TBARS (nmoles/mg protein) 0.85 ± 0.03 1.18 ± 0.05c 0.94 ± 0.06d 0.89 ± 0.07d
protein carbonyls (nmoles/mg protein) 1.08 ± 0.05 1.62 ± 0.09b 1.49 ± 0.12 1.53 ± 0.07
NP-TSH (nmoles/mg tissue) 1.99 ± 0.09 1.66 ± 0.08b 1.86 ± 0.08 1.81 ± 0.09
mucin (μg/g tissue) 335.03 ± 14.43 213.02 ± 0.59b 240.33 ± 20.49 253.33 ± 14.53d
  1. aStomach ulceration in mice was induced by oral administration of indomethacin (18 mg/kg). PK (20 mg/kg/day × 1 day) and Omez (3 mg/kg/day × 1 day) were used as the test samples. The assays were carried out 4 h after the administration of the test samples. The values are mean ± SEM (n = 15). b P < 0.05, c P < 0.01 compared to normal mice; d P < 0.05 compared to the group II mice.