Oral treatment (n = 8) | Liver glycogen g/100 g | Glucose uptake by hemidiaphragm mg/100 mg | Glucose transfer by liver mg/g | Pancreas histoarchetechture necrotic changes & persistence of islets of Langerhans* |
---|---|---|---|---|
 | Mean ± SEM | |||
Normal control | 3.8 ± 0.4 | 16.0 ± 0.4 | 26.9 ± 0.4 | 0.3 ± 0.01 |
Diabetic control | 1.0 ± 0.2# | 4.7 ± 0.2# | 42.6 ± 2.2# | 3.6 ± 0.13 |
MCE (150 mg/kg) | 1.6 ± 0.2b | 8.1 ± 0.3a | 17.9 ± 0.4a | 2.9 ± 0.2 |
MCE (300 mg/kg) | 1.7 ± 0.1a | 15.9 ± 0.4a | 15.6 ± 0.7a | 1.9 ± 0.12 |
Glibenclamide 4 mg/kg | 1.8 ± 0.1a | 14.0± 0.3a | 17.9 ± 0.8a | 1.8 ± 0.18 |