The cytotoxic effects of Scutellaria baicalensis extract on normal glial cells and glioma cells. Wells were essentially confluent at the beginning of the experiment. (A) Metabolic activity of normal glial cells (HJ) and cells from a recurrent tumor (MER) were measured using the AlamarBlue™ metabolic assay. Glioma cells were cultured with 100 μg/ml of the S. baicalensis extract for approximately 48 hours. Results were presented as a percentage of the control (untreated). Data show means ± SD of 3 replicates. (B) Photomicrographs of cells 48 hours following treatment with 100 μg/ml of S. baicalensis extract.