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Table 3 Effects of total chikusetsusaponins and orlistat (a lipase inhibitor) on liver weight, hepatic triacylglycerol, and adipose tissue weight in mice fed a high-fat diet for 9 weeks.

From: Anti-obesity effects of chikusetsusaponins isolated from Panax japonicus rhizomes

  Animal No. Liver weight (g/100 g body weight) Hepatic triacylglycerol (μmol/g) Parametrial adipose tissue weight (g)
Laboratory chow pellet 26 5.20 ± 0.46* 22.3 ± 2.3* 0.71 ± 0.1*
High-fat diet (HF) 26 6.35 ± 0.76 141.8 ± 21.8 1.59 ± 0.3
HF +     
1% Total saponins 11 6.13 ± 0.79 101.5 ± 6.8* 0.87 ± 0.1*
HF +     
3% Total saponin 11 5.79 ± 0.47* 83.3 ± 6.7* 0.74 ± 0.1*
HF + 0.012% Orlistat 15 4.00 ± 0.11* 101.1 ± 4.8* 2.03 ± 0.12
  1. Values are means ± S.E. of 11 – 26 mice. *Significantly different from the high-fat diet group, P < 0.05.