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Table 2 Clinical complications and side effects were reported as number per group.

From: Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial [ISRCTN45683816]

Side Effects Saffron Imipramine P
Anxiety 4 1 0.32
Decreased Appetite 2 0 0.48
Increased Appetite 1 5 0.16
Sedation 0 6 0.01
Nausea 2 1 1.00
Headache 3 2 1.00
Dry Mouth 1 7 0.03
Hypomania 2 1 1.00
Constipation 2 5 038
Urinary Retention 1 5 0.16