Table 2 Effect of Paederia foetida Linn. on biochemical parameters in STZ-induced diabetic rats

1

Fasting plasma glucose (mg/dL)

81.8 ± 0.201

79.8 ± 0.245

348.4 ± 2.781^a

154.2 ± 1.812^b

133.2 ± 0.861^b

107.6 ± 1.749^b

122 ± 1.844^b

2

Fasting Plasma Insulin (μU/mL)

11.4 ± 0.509

11.4 ± 0.245

2.4 ± 0.453^a

4.2 ± 0.373^b

6.2 ± 0.374^b

10.6 ± 0.438^b

9.6 ± 0.123^b

3

Glycated Heamoglobin (A1c) (%)

1.24 ± 0.092

1.24 ± 0.0812

4.86 ± 0.178^a

3.96 ± 0.238^b

2.82 ± 0.861^b

1.52 ± 0.0431^b

1.86 ± 0.093^b

4

Hexokinase (μg/mg of tissue)

151 ± 3.24

150.6 ± 3.108

88.4 ± 1.806^a

115.2 ± 1.497^b

131 ± 1.643^b

147.2 ± 1.281^b

141.6 ± 2.088^b

5

Glucose-6-Phosphatase (unit/mg of tissue)

8 ± 0.707

8 ± 0.717

14.4 ± 0.927^a

13.4 ± 0.509^b

11.4 ± 0.432^b

8.4 ± 0.436^b

9.8 ± 0.374^b

6

Fructose-1-6-biphosphatase (unit/mg of tissue)

26.8 ± 1.241

27 ± 1.517

54.8 ± 1.281^a

43 ± 1.871^b

38.2 ± 1.497^b

30 ± 0.707^b

31 ± 0.431^b

7

Total Cholesterol (mg/dL)

66.2 ± 1.715

66.8 ± 1.393

141.2 ± 2.634^a

129.8 ± 1.53^b

101.8 ± 1.934^b

76.2 ± 2.01^b

84 ± 2.302^b

8

Triglycerides (mg/dL)

78 ± 1.975

78.2 ± 1.431

144.8 ± 3.04^a

131 ± 1.789^b

110.2 ± 1.828^b

91 ± 1.703^b

98 ± 1.265^b

9

Total HDL Cholesterol (mg/dL)

57 ± 1.14

57 ± 0.124

25.4 ± 1.208^a

39 ± 1.225^b

44.4 ± 1.03^b

51.6 ± 0.927^b

53.4 ± 0.927^b

10

Total LDL Cholesterol (mg/dL)

6.4 ± 0.18

6.8 ± 0.431

86.8 ± 0.818^a

64.6 ± 0.053^b

35.4 ± 0.538^b

8.4 ± 1.121^b

11 ± 0.742^b

11

Total VLDL Cholesterol (mg/dL)

15.6 ± 0.295

15.72 ± 0.132

28.96 ± 0.608^a

26.2 ± 0.375^b

22 ± 0.365^b

18.2 ± 0.253^b

10.6 ± 0.341^b