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Table 2 Effect of RMO on writhing induced by acetic acid and formalin-induced nociception tests

From: Chemical composition, antinociceptive, anti-inflammatory and redox properties in vitro of the essential oil from Remirea maritima Aubl. (Cyperaceae)

Treatment Dose (mg/kg) Writhing test Formalin test
Number of writhingsa 0-5 mina 15-30 mina
Vehicle - 32.8 ± 2.8 56.3 ± 5.2 115.0 ± 8.7
RMO 50 20.6 ± 2.3b 43.0 ± 2.92 54.5 ± 4.5d
RMO 100 18.1 ± 3.6c 39.0 ± 3.0 54.8 ± 4.3d
RMO 200 10.1 ± 2.5d 31.3 ± 5.69c 38.6 ± 3.6d
Aspirin 200 3.5 ± 1.7d 40.1 ± 4.9 35.4 ± 8.9d
  1. n = 8, per group.
  2. aValues represent mean ± S.E.M.
  3. bp < 0.05, cp < 0.01 and dp < 0.001 (one-way ANOVA and Tukey’s test), significantly different from control group.