Brain regions involved in moxibustion-induced analgesia in irritable bowel syndrome with diarrhea: a functional magnetic resonance imaging study

Table 4 Rectal distention threshold comparison

Item	First sensation threshold						Defecation urge threshold						Pain detection threshold
	Before Treatment		After Treatment		Difference		Before Treatment		After Treatment		Difference		Before Treatment		After Treatment		Difference
	Mean ± S.E	95% CI	Mean ± S.E	95% CI	Mean ± S.E	95% CI	Mean ± S.E	95% CI	Mean ± S.E	95% CI	Mean ± S.E	95% CI	Mean ± S.E	95% CI	Mean ± S.E	95% CI	Mean ± S.E	95% CI
Moxibustion group (n = 15)	22.27 ± 2.052	[21.13,23.40]	22.67 ± 0.63	[21.32,24.0]	0.40 ± 0.81	[−1.34,2.14]	40.07 ± 3.23	[33.13,47.00]	63.47 ± 2.01^▲	[59.15,67.78]	23.40 ± 2.88^★	[17.23,29.57]	89.07 ± 5.01	[78.33,99.81]	113.6 ± 7.51^●	[97.48,129.72]	24.53 ± 5.78^○	[12.14,36.92]
Control group (n = 13)	22.31 ± 3.351	[20.28,24.33]	21.69 ± 1.17	[19.14,24.2]	−0.62 ± 1.5	[−0.43,2.80]	41.31 ± 1.89	[37.19,45.42]	44.15 ± 1.55	[40.78,47.58]	2.85 ± 1.68	[−0.80,6.50]	89.62 ± 2.85	[83.41,95.82]	93.46 ± 2.67	[87.64,99.28]	3.85 ± 2.84	[−2.33,10.02]

Compared with baseline, ▲ p = 0.000, compared with the control group, ▲ p = 0.000, ★ p = 0.000.
Compared with baseline, ● p = 0.001, compared with the control group, ● p = 0.022, ○ p = 0.005.

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