Effect of antibiotics, PHY906, CPT-11 and PHY906/CPT-11(9/c) on intestinal bacteria densities in murine Colon-38 tumor-bearing BDF1 micex. (A) Quantitative PCR heat maps for Lactobacillus/Enterococcus (Lact), Bacteroides (Bact), Clostridium leptum (Clept) and E. rectale/C. coccoides (Erec). The abundance of bacteria is categorized from high (red) to low (green) as indicated by the bar on the right side of the table. The top of the bar (100%) indicates the highest density of each bacterial group at each row of the table. (B-J) Quantitative PCR results for Lact, Bact, Clept and Erec in the middle jejunum (MJ) and colon. Each spot represents a mean of two or three different quantitative real-time PCR experiments (triplicate samples of each; 5 animals in each treatment group). Student's t-test was used to determine whether differences between treatment groups were significant. Details of experimental procedures are given in Methods.