Protective effect of VE against DM-induced DNA damage in rat’s brain. (a) DNA fragmentation % by DPA assay; control (I), DM-treated group (II), DM + VE group (III) and VE group (IV). (b) The electrophoretic pattern of small DNA fragments on 1.5% agarose gel electrophoresis. Control group (lanes 1, 2) vitamin E control group (lanes 3, 4) DM group (lanes 5, 6) and DM + VE treated group (lanes 7 and 8) M 100 bp DNA marker. Values are expressed as mean ± S.E. Different superscripts letters represents significant difference (p < 0.05).