Figure 7
From: Antiproliferative effect of the jararhagin toxin on B16F10 murine melanoma
Cell cycle analysis of B16F10 cells treated with jara and jari. Cells were stained with iodide propidium for DNA content analysis by flow cytometry. The bars represent the proportions of G2/M proliferative cells; in phase S synthesis; G0/G1 quiescent cell, and debris in sub-G1. The figure shows a significant decrease in the percentage of cells in G0/G1 phase and a subsequent increase in sub-G1 phase with increased concentration of jara and jari. Data represents mean ± SD from three independent experiments. *Significantly different from control *p < 0.05; **p < 0.01 and ***p < 0.001.