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Table 3 Time-course effects of EA intervention on the expressions of Ang II, AT 1 R, and AT 2 R after MCAO as determined by immunohistochemistry assay (IOD)

From: Electroacupuncture improves cerebral blood flow and attenuates moderate ischemic injury via Angiotensin II its receptors-mediated mechanism in rats

Time h Model group EA group
  AngII AT1R AT2R AngII AT1R AT2R
1 2.139 ± 0.295 2.768 ± 0.454 1.912 ± 0.484 1.746 ± 0.336** 2.474 ± 0.428※* 2.373 ± 0.487**
2 2.200 ± 0.177 2.777 ± 0.222 1.952 ± 0.505 1.928 ± 0.268** 2.317 ± 0.409※** 2.501 ± 0.449※**
3 2.259 ± 0.215 2.496 ± 0.145 2.455 ± 0.297 2.003 ± 0.287** 2.191 ± 0.553※* 2.780 ± 0.339※**
6 2.330 ± 0.528 2.425 ± 0.396 2.526 ± 0.632 2.634 ± 0.474※** 1.956 ± 0.366※** 2.885 ± 0.583※*
9 2.667 ± 0.383 2.379 ± 0.496 2.599 ± 0.454 2.901 ± 0.344※* 2.057 ± 0.438※* 3.117 ± 0.412※**
12 2.889 ± 0.257 2.595 ± 0.281 2.484 ± 0.533 3.108 ± 0.193※* 2.351 ± 0.193※** 3.155 ± 0.443※**
15 2.773 ± 0.344 2.604 ± 0.262 2.661 ± 0.428 3.226 ± 0.210※* 2.337 ± 0.475※* 3.346 ± 0.295※**
18 2.754 ± 0.245 2.657 ± 0.280 2.539 ± 0.618 3.012 ± 0.308※** 2.448 ± 0.366※* 2.997 ± 0.594※*
21 2.376 ± 0.542 2.744 ± 0.436 2.400 ± 0.623 2.669 ± 0.479※* 2.526 ± 0.257※* 2.882 ± 0.588※**
24 2.474 ± 0.463 2.697 ± 0.321 2.445 ± 0.494 3.233 ± 0.335※** 2.365 ± 0.400※** 2.817 ± 0.513※*
  1. EA: Electroacupuncture; Ang II: Angiotensin II; AT1R: Ang II type 1 receptor; AT2R: Ang II type 2 receptor; p < 0.05 vs the control group (values were 1.872 ± 0.331 for AngII, 2.037 ± 0.307 for AT1R, and 2.091 ± 0.451 for AT2R), * p < 0.05, ** p < 0.01 vs model group at the same time points.