Effects of Cx43 siRNA or scrambled siRNA on cell proliferation in HOCC treated with G. lucidum. Cells were collected before (day 0) and 3 days after co-treatment with G. lucidum and siRNAs. Data are shown as mean ± S.D. of three independent experiments. *P < 0.05 vs respective day 0; †P < 0.05 vs corresponding control or scrambled group.