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Table 2 Cytotoxicity results of A.carnosus extracts by SRB assay

From: Cytotoxic potential of Anisochilus carnosus (L.f.) wall and estimation of luteolin content by HPLC

Concentration (μg/ml)

% Viability

Aqueous extract

Ethanolic extract

Pet. ether extract

Paclitaxel

0

100 ± 6.198

100 ± 6.198

100 ± 6.198

100 ± 2.44

6.25

-

-

-

86.25 ± 0.441**

12.5

-

-

-

45.36 ± 0.582**

25

89.50 ± 0.883

80.57 ± 1.972*

46.68 ± 5.838**

29.51 ± 1.54**

50

71.01 ± 2.141**

59.04 ± 3.507**

36.89 ± 3.525**

16.46 ± 2.313**

100

61.44 ± 1.129**

36.38 ± 1.396**

18.73 ± 2.505**

-

200

52.43 ± 0.745**

11.85 ± 2.371**

10.84 ± 2.741**

-

IC 50 value

211.26

87.24

22.5a

13.91a

  1. Results were expressed as Mean ± SEM (n = 3) and analysed using one-way ANOVA followed by Tukey’s post hoc test of significance [where different alphabets a, b denote significant difference (p <0.05)]. Statistical comparison between the mean % viability of each extract and its negative control was performed using one-way ANOVA followed by Dunnett’s post hoc test of significance wherein *p <0.05 and **p <0.01 were considered to be statistically significant and very statistically significant compared to negative control. A.carnosus extracts were not tested at concentrations of 200, 100, 50, 25 μg/ml (they were not tested at concentrations of 6.25 and 12.5 μg/ml). Paclitaxel was tested at concentrations of 6.25, 12.5, 25 and 50 μg/ml.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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