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Table 1 Results of the antifungal activities of the bulbs extract and its pure alkaloids

From: Relevant and selective activity of Pancratium illyricum L. against Candida albicans clinical isolates: a combined effect on yeast growth and virulence

  Antifungal activities
experimental IC50(μg/mL) endpoint IC50(μg/mL) MIC (μg/mL)
P. illyricum bulbs 0.65 – 47 1.22 - 78 19.5 - 156
Lycorine 0.46 – 16.95 0.89 – 28.50 3.56 – 57
Vittatine - - -
Amphotericin B 0.02 – 0.23 0.039 – 0.625 0.078 – 1.25
  1. The following range concentrations were used in the microdilution broth methods: from 312 to 0.156 μg/mL for P. illyricum bulbs, from 114 to 0.03 μg/mL for lycorine; from 225 to 0.05 μg/mL for vittatine and from 5 to 0.002 μg/mL for amphotericin B.
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