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Table 1 Results of the antifungal activities of the bulbs extract and its pure alkaloids

From: Relevant and selective activity of Pancratium illyricum L. against Candida albicans clinical isolates: a combined effect on yeast growth and virulence

 

Antifungal activities

experimental IC50(μg/mL)

endpoint IC50(μg/mL)

MIC (μg/mL)

P. illyricum bulbs

0.65 – 47

1.22 - 78

19.5 - 156

Lycorine

0.46 – 16.95

0.89 – 28.50

3.56 – 57

Vittatine

-

-

-

Amphotericin B

0.02 – 0.23

0.039 – 0.625

0.078 – 1.25

  1. The following range concentrations were used in the microdilution broth methods: from 312 to 0.156 μg/mL for P. illyricum bulbs, from 114 to 0.03 μg/mL for lycorine; from 225 to 0.05 μg/mL for vittatine and from 5 to 0.002 μg/mL for amphotericin B.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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