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Table 3 Chemical analysis of serums obtained from mice administrated with 600 mg/Kg of GBT

From: Guibitang, a traditional herbal medicine, induces apoptotic death in A431 cells by regulating the activities of mitogen-activated protein kinases

Treat. GOT (IU/L) GPT (IU/L) ALP (IU/L) LDH (IU/L) UREA (mg/dL) CRE (mg/dL)
Vehicle 54.0 ± 3.5 28 ± 0.0 48.0 ± 22.3 420.0 ± 65.8 27.9 ± 7.6 1.0 ± 0.0
GBT 41.3 ± 4.6 26 ± 0.0 30.7 ± 21.9 319.3 ± 94.7 27.5 ± 0.2 1.0 ± 0.0
  1. Each group of mice (n=5) was treated orally with 600 mg/Kg GBT for 14 days. The levels of GOT, GPT, ALP, LDH, BUN, and CRE were analyzed to confirm the cytotoxic effects of GBT. Data are expressed as mean ± S.D.
  2. GOT, glutamic oxaloacetic transaminase; GBT, glutamic puruvic transaminase; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; BUN, blood urea nitrogen; CRE, creatinine.