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Table 1 Antibacterial activity of crude extract and fractions of Phytolacca americana against the tested bacteria

From: Antibacterial effect of crude extract and metabolites of Phytolacca americana on pathogens responsible for periodontal inflammatory diseases and dental caries

Plant fractions Concentration P. gingivalis S. mutans E. coli DH5α
  Growth inhibition (%)
Crude extract 0.2 mg/mL 88 ± 19.06b*# 13 ± 21.66yz 2 ± 3.94
  0.6 mg/mL 100 ± 0.39a 35 ± 25.01xy 3 ± 3.20
  1.8 mg/mL 100 ± 0.41a 44 ± 35.29x 6 ± 4.45
  MIC 0.2 mg/mL 1.8 mg/mL -
Hexane Fr. 0.008 mg/mL 0 ± 0.00e 2 ± 16.46z 0 ± 0.00
  0.04 mg/mL 26 ± 2.36d 0 ± 0.00z 0 ± 0.00
  0.2 mg/mL 92 ± 0.56ab 62 ± 1.49x 0 ± 0.00
  MIC 0.2 mg/mL 0.2 mg/mL -
CHCl3 Fr. 0.008 mg/mL 0 ± 0.00e 0 ± 0.00z 0 ± 0.00
  0.04 mg/mL 0 ± 0.00e 0 ± 0.00z 0 ± 0.00
  0.2 mg/mL 91 ± 2.00ab 56 ± 10.52x 0 ± 0.00
  MIC 0.2 mg/mL 0.2 mg/mL -
EtOAc Fr. 0.008 mg/mL 0 ± 0.00e 0 ± 0.00z 7 ± 1.90
  0.04 mg/mL 0 ± 0.00e 1 ± 0.00z 2 ± 1.38
  0.2 mg/mL 46 ± 5.63c 0 ± 0.00z 0 ± 0.00
BuOH Fr. 0.008 mg/mL 0 ± 0.00e 0 ± 0.00z 10 ± 0.83
  0.04 mg/mL 0 ± 0.00e 0 ± 0.00z 6 ± 1.05
  0.2 mg/mL 4 ± 1.55e 0 ± 0.00z 0 ± 0.00
  1. *Data are expressed as the mean ± SD.
  2. #Values in the same column with different superscript letters are significantly different (p < 0.001).
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