Table 1 Cytotoxicity of the studied Aframomum extracts, compounds and doxorubicin towards sensitive and drug-resistant cancer cell lines and normal cells as determined by the resazurin assay

20.37 ± 3.10

18.08 ± 0.98

17.32 ± 1.96

19.81 ± 2.01

12.20 ± 1.87

18.38 ± 2.04

0.11 ± 0.01

28.16 ± 1.24 (1.38)

13.73 ± 1.02 (0.76)

- (>2.31)

- (>2.02)

7.86 ± 0.74 (0.64)

18.22 ± 1.18 (0.99)

195.12 ± 14.30 (1772)

33.79 ± 2.38

29.98 ± 1.86

-

-

9.51 ± 1.03

-

1.10 ± 0.01

30.24 ± 2.18 (0.89)

30.66 ± 3.17 (1.02)

27.99 ± 2.39 (<0.70)

-

18.12 ± 2.01 (1.91)

33.14 ± 2.64 (<0.83)

7.83 ± 0.01 (7.11)

-

23.06 ± 2.21

-

-

13.65 ± 1.11

-

1.43 ± 0.02

-

27.38 ± 1.92 (1.19)

-

-

13.86 ± 0.94 (1.02)

36.74 ± 2.31 (<0.82)

4.06 ± 0.04 (2.84)

-

36.70 ± 2.12

-

-

29.81 ± 1.88

-

1.06 ± 0.03

20.59 ± 1.87 (<0.51)

24.42 ± 1.95 (0.67)

-

-

18.02 ± 1.34 (0.60)

-

6.11 ± 0.04 (5.76)

-

23.15 ± 1.97 (<0.58)

-

-

23.46 ± 1.95 (<0.59)

-

1.41 ± 0.12 (<0.04)

-

-

-

-

-

-

-