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Table 3 Chromatographic profile and activity of seventeen fractions from ML LMeOH on microfilariae motility

From: In vitro anti-Onchocerca ochengi activities of extracts and chromatographic fractions of Craterispermum laurinum and Morinda lucida

Eluent Combined Fractions:code % inhibition of microfilariae motility on day 5 concentration of extracts (μg/ml)  
Hex:EtOAc 500 250 125 62.5 31.25 15.63 7.8 0 IC50of mfs
100:0 1-13: MLM1 100 50 0 0 0 0 0 0 250
95:5 14-16: MLM2 50 0 0 0 0 0 0 0 500
17-24: MLM3 100 100 50 0 0 0 0 0 125
90:10 25-32: MLM4 50 0 0 0 0 0 0 0 500
80:20 33-40: MLM5 100 75 0 0 0 0 0 0 187.5
41-49: MLM6 50 25 0 0 0 0 0 0 500
70:30 50-54: MLM7 100 75 50 0 0 0 0 0 125
55-61: MLM8 100 100 100 50 25 0 0 0 62.5
60:40 62-65: MLM9 100 100 100 100 50 0 0 0 31.25
66-74: MLM10 100 100 100 100 100 100 50 0 7.8
50:50 75-86: MLM11 100 100 100 100 50 50 25 0 15.63
40:60 87-100:MLM12 100 100 100 50 0 0 0 0 62.5
20:80 101-109:MLM13 100 100 100 100 100 25 0 0 23.44
110-117:MLM14 100 100 100 100 50 0 0 0 31.25
CH2Cl2:MeOH           
95:5 118-120:MLM15 100 100 100 50 25 25 25 0 62.5
121-128:MLM16 75 50 25 0 0 0 0 0 250
90:10 129-150:MLM17 100 50 0 0 0 0 0 0 250
80:20
70:30
60:40
  1. MLM: M. lucida leaves. The 0 μg/ml are the negative control wells with 2% DMSO.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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