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Table 2 Effect produced by administration of the essential oil of Foeniculum vulgare and reference compounds to mice in the staircase test

From: Evaluation of anxiolytic activity of the essential oil of the aerial part of Foeniculum vulgare Miller in mice

Treatment

Dose (mg/kg)

Number of rearing

Number of stairs climbed

Vehicle

-

19.67 ± 2.50

16.17 ± 6.11

FV

50

15.00 ± 1.67 d**

18.00 ± 4.19 e**

FV

100

13.33 ± 4.93a* d*

13.34 ± 1.37

FV

200

8.00 ± 3.03 (a, b, e)**. (c, f)*

11.50 ± 3.56

FV

400

18.33 ± 3.44 d**

9.50 ± 4.09 a*. b**

Diazepam

0.5

14.00 ± 3.29(a*.d*)

12.00 ± 4.56

  1. Data are mean ± S.E.M, n = 6, acompared with vehicle, bto 50 mg/kg, cto 100 mg/kg, dto 200 mg/kg, eto 400 mg/kg, fto diazepam, *P < 0.05, **P < 0.01. FV = Foeniculum vulgare essential oil.