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Table 4 Effect of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on body weight variation (grams) in normal & STZ induced diabetic treated rats

From: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups Time (h)
1st Day 45th Day
Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1 245.6 ± 4.479 297 ± 2.408
Diabetic control (administered with Streptozotocin (STZ) Group 2 249.8 ± 3.625 217.2 ± 3.527
Diabetic control + (ALEx) (100 mg/kg body weight) Group 3 245.6 ± 1.965ns 236 ± 2.702
Diabetic control + (ALEx) (200 mg/kg body weight) Group 4 247.4 ± 1.288 247.2 ± 2.417
Diabetic control + (ALEx) (300 mg/kg body weight) Group 5 247.2 ± 3.680 266 ± 0.7071
Diabetic control + (ALEx) (400 mg/kg body weight) Group 6 252.2 ± 2.245** 300 ± 0.5099**
Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7 249.8 ± 1.020 302 ± 0.7071***
  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. **p < 0.001 is considered as very significant when compared to the control group (0 h).
  4. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).