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Table 4 Effect of methanol/dichloromethane extract ofAlbizzia Lebbeck Benth.stem bark (ALEx) on body weight variation (grams) in normal & STZ induced diabetic treated rats

From: RETRACTED ARTICLE: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Groups

Time (h)

1st Day

45th Day

Normal rats (untreated with dimethylsulfoxide, [DMSO]) Group 1

245.6 ± 4.479

297 ± 2.408

Diabetic control (administered with Streptozotocin (STZ) Group 2

249.8 ± 3.625

217.2 ± 3.527

Diabetic control + (ALEx) (100 mg/kg body weight) Group 3

245.6 ± 1.965ns

236 ± 2.702

Diabetic control + (ALEx) (200 mg/kg body weight) Group 4

247.4 ± 1.288

247.2 ± 2.417

Diabetic control + (ALEx) (300 mg/kg body weight) Group 5

247.2 ± 3.680

266 ± 0.7071

Diabetic control + (ALEx) (400 mg/kg body weight) Group 6

252.2 ± 2.245**

300 ± 0.5099**

Diabetic control + Glibenclamide (1 mg/kg b wt.) Group 7

249.8 ± 1.020

302 ± 0.7071***

  1. The data are expressed as mean ± SEM. (n = number of animals in each group = 5). The comparisons were made by one way ANOVA followed by Dunnent’s test.
  2. ns = non-significant, STZ = Streptozotocin.
  3. **p < 0.001 is considered as very significant when compared to the control group (0 h).
  4. ***p < 0.001 is considered as extremely significant when compared to the control group (0 h).