Figure 12
Effect of Albizia Lebbeck Benth. stem bark extract (ALEx) on histological profile of heart in normal, STZ-induced diabetic untreated and STZ-induced diabetic treated wistar rats (Original magnification 40×, DXIT 1200 , Nikon, Japan). (i) NHALx: Heamatoxylin and eosin (H/E) stained sections of heart (oblique cut) of normal control rats showing well arranged cardiac myocytes and normal striations (yellow arrows). (ii) STZH: Section of heart of STZ-induced diabetic rats depicting disarranged cardiac myocytes with destroyed striations (yellow arrows). (iii) ALEx100: Cardiac section of rats received 100 mg/kg body wt. of ALEx portraying better striations (yellow arrows). (iv) ALEx200: Heart section of diabetic rats administered with 200 mg/kg body wt. of ALEx showing improved arrangement of cardiac myocytes (yellow arrows). (v) ALEx 300: Section of heart of diabetic rats supplemented with 300 mg/kg body wt. of ALEx, showing nearly normal cardiac myocytes and striations (yellow arrows). (vi) ALEx400: H/E stained section of heart of diabetic rats received 400 mg/kg body wt. of ALEx depicting normal arrangement of cardiac myocytes and normal striations (yellow arrows). HGLB: Heart section of diabetic rats administered with Glibenclamide portraying normal cardiac myocytes (yellow arrows).