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Figure 12 | BMC Complementary and Alternative Medicine

Figure 12

From: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. stem bark (ALEx) on streptozotocin induced diabetic rats

Figure 12

Effect of Albizia Lebbeck Benth. stem bark extract (ALEx) on histological profile of heart in normal, STZ-induced diabetic untreated and STZ-induced diabetic treated wistar rats (Original magnification 40×, DXIT 1200 , Nikon, Japan). (i) NHALx: Heamatoxylin and eosin (H/E) stained sections of heart (oblique cut) of normal control rats showing well arranged cardiac myocytes and normal striations (yellow arrows). (ii) STZH: Section of heart of STZ-induced diabetic rats depicting disarranged cardiac myocytes with destroyed striations (yellow arrows). (iii) ALEx100: Cardiac section of rats received 100 mg/kg body wt. of ALEx portraying better striations (yellow arrows). (iv) ALEx200: Heart section of diabetic rats administered with 200 mg/kg body wt. of ALEx showing improved arrangement of cardiac myocytes (yellow arrows). (v) ALEx 300: Section of heart of diabetic rats supplemented with 300 mg/kg body wt. of ALEx, showing nearly normal cardiac myocytes and striations (yellow arrows). (vi) ALEx400: H/E stained section of heart of diabetic rats received 400 mg/kg body wt. of ALEx depicting normal arrangement of cardiac myocytes and normal striations (yellow arrows). HGLB: Heart section of diabetic rats administered with Glibenclamide portraying normal cardiac myocytes (yellow arrows).

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