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Table 4 Total symptom scores in Xuan Bai Cheng Qi and control groups during 10 - day treatment

From: Xuan Bai Cheng Qi formula as an adjuvant treatment of acute exacerbation of chronic obstructive pulmonary disease of the syndrome type phlegm-heat obstructing the lungs: a multicenter, randomized, double-blind, placebo-controlled clinical trial

Total symptom scores Full analysis set Per - protocol analysis set
  XBCQa Controla Treatment effectb XBCQa Controla Treatment effectb
  (n = 122) (n = 122) (95% CI;P-value) (n = 122) (n = 122) (95% CI;P- value)
1 d 19.70 (4.23) 20.10 (4.28) -0.39 (-1.47, 0.68; .471) 19.64 (4.24) 20.09 (4.32) -0.45 (-1.56, 0.67; .433)
3 d 13.92 (4,46) 16.48 (4.08) -2.57 (-3.64, -1.49; < .001) 13.82 (4.50) 16.42 (3.95) -2.60 (-3.70, -1.49; < .001)
5 d 10.64 (4.28) 13.20 (4.18) -2.56 (-3.63, -1.49; < .001) 10.59 (4.24) 13.12 (4.10) -2.52 (-3.61, -1.44; < .001)
7 d 7.72 (4.34) 9.64 (3.68) -1.92 (-2.93, -0.90; < .001) 7.64 (4.38) 9.54 (3.65) -1.90 (-2.95, -0.86; < .001)
10 d 5.21 (4.43) 7.00 (3.72) -1.79 (-2.82, -0.76; 0.001) 5.03 (4.29) 6.92 (3.74) -1.89 (-2.93, -0.84; < .001)
Meanc 11.44 (3.36) 13.28 (3.09) -1.84 (-2.66, -1.03; < .001) 11.34 (3.40) 13.22 (3.05) -1.87 (-2.71, -1.03; < .001)
  1. Abbreviations: CI confidence interval, XBCQ Xuan Bai Cheng Qi.
  2. Mauchly’s test of sphericity was applied: W = .506, P < .001.
  3. aData presented as mean (SD).
  4. bRepeated-measures analysis of variance (ANOVA) for estimate with 95% confidence interval for difference.
  5. cMean = change from baseline.