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Table 4 Total symptom scores in Xuan Bai Cheng Qi and control groups during 10 - day treatment

From: Xuan Bai Cheng Qi formula as an adjuvant treatment of acute exacerbation of chronic obstructive pulmonary disease of the syndrome type phlegm-heat obstructing the lungs: a multicenter, randomized, double-blind, placebo-controlled clinical trial

Total symptom scores

Full analysis set

Per - protocol analysis set

 

XBCQa

Controla

Treatment effectb

XBCQa

Controla

Treatment effectb

 

(n = 122)

(n = 122)

(95% CI;P-value)

(n = 122)

(n = 122)

(95% CI;P- value)

1 d

19.70 (4.23)

20.10 (4.28)

-0.39 (-1.47, 0.68; .471)

19.64 (4.24)

20.09 (4.32)

-0.45 (-1.56, 0.67; .433)

3 d

13.92 (4,46)

16.48 (4.08)

-2.57 (-3.64, -1.49; < .001)

13.82 (4.50)

16.42 (3.95)

-2.60 (-3.70, -1.49; < .001)

5 d

10.64 (4.28)

13.20 (4.18)

-2.56 (-3.63, -1.49; < .001)

10.59 (4.24)

13.12 (4.10)

-2.52 (-3.61, -1.44; < .001)

7 d

7.72 (4.34)

9.64 (3.68)

-1.92 (-2.93, -0.90; < .001)

7.64 (4.38)

9.54 (3.65)

-1.90 (-2.95, -0.86; < .001)

10 d

5.21 (4.43)

7.00 (3.72)

-1.79 (-2.82, -0.76; 0.001)

5.03 (4.29)

6.92 (3.74)

-1.89 (-2.93, -0.84; < .001)

Meanc

11.44 (3.36)

13.28 (3.09)

-1.84 (-2.66, -1.03; < .001)

11.34 (3.40)

13.22 (3.05)

-1.87 (-2.71, -1.03; < .001)

  1. Abbreviations: CI confidence interval, XBCQ Xuan Bai Cheng Qi.
  2. Mauchly’s test of sphericity was applied: W = .506, P < .001.
  3. aData presented as mean (SD).
  4. bRepeated-measures analysis of variance (ANOVA) for estimate with 95% confidence interval for difference.
  5. cMean = change from baseline.