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Table 3 Body weight changes of Micronucleus test in mice following administration of Guibi-Tang (GBT) extract

From: Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test

Group Vehicle control GBT GBT GBT Positive control
Dose (mg/kg) 0 500 1000 2000 70
Day 1 (Mean ± S.D) 34.6 ± 0.79 34.7 ± 1.34 34.8 ± 1.14 35.1 ± 0.57 35.5 ± 0.63
Day 2 (Mean ± S.D) 34.9 ± 1.42 35.2 ± 1.21  35.2 ± 1.19 35.3 ± 0.96 35.3 ± 0.40
Day 3 (Mean ± S.D) 34.8 ± 1.04 35.5 ± 1.11  35.2 ± 0.72 35.0 ± 0.69 34.5 ± 0.67