Figure 2

Histological features of patched skin in BALB/c mice. Mice were epicutaneously sensitized and fed as shown in Figure 1. (A) Marked thickening of the epidermis with mild spongiosis and inflammatory cell infiltration in the dermis. (B) Epidermal thickness was determined in each of the 3 groups of mice. Data are presented as the mean ± standard error of the mean (SEM) and performed with one-way analysis of variance (ANOVA) followed by Tukey’s multiple comparison test to compare each group. All p-values less than 0.05 were considered statistically significant.