From: Mutagenicity and antimutagenicity of six Brazilian Byrsonima species assessed by the Ames test
Treatment (mg/plate) | TA98 | Treatment (mg/plate) | TA100 | Treatment (mg/plate) | TA97a | Treatment (mg/plate) | TA102 | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
- S9 | + S9 | - S9 | + S9 | - S9 | + S9 | - S9 | + S9 | ||||
B. verbascifolia | |||||||||||
0.0 a | 17 ± 4 | 68 ± 1 | 0.0 a | 113 ± 16 | 114 ± 11 | 0.0 a | 81 ± 6 | 121 ± 20 | 0.0 a | 381 ± 43 | 341 ± 34 |
2.1 | 15 ± 3 (0.9) | 67 ± 2 (1.0) | 0.4 | 91 ± 8 (0.8) | 121 ± 12 (1.1) | 0.2 | 78 ± 3 (1.0) | 137 ± 16 (1.1) | 0.4 | 369 ± 3 (1.0) | 387 ± 20 (1.1) |
4.2 | 24 ± 6 (1.4) | 75 ± 5 (1.1) | 0.7 | 107 ± 20 (1.0) | 124 ± 10 (1.1) | 0.4 | 97 ± 2 (1.2) | 140 ± 10 (1.2) | 0.7 | 305 ± 16 (0.8) | 445 ± 32 (1.3) |
8.3 | 18 ± 6 (1.0) | 81 ± 3 (1.2) | 1.5 | 106 ± 2 (0.9) | 99 ± 4 (0.9) | 0.8 | 117 ± 2 (1.4) | 146 ± 7 (1.2) | 1.5 | 368 ± 36 (1.0) | 353 ± 29 (1.0) |
12.5 | 23 ± 3 (1.3) | 61 ± 4 (0.9) | 2.2 | 105 ± 4 (0.9) | 104 ± 5 (0.9) | 1.1 | 109 ± 6 (1.3) | 166 ± 12 (1.4) | 2.2 | 322 ± 45 (0.9) | 344 ± 45 (1.0) |
16.7 | 29 ± 12 (1.7) | 50 ± 1 (0.7) | 3.0 | 110 ± 9 (1.0) | 93 ± 3 (0.8) | 1.6 | 94 ± 5 (1.2) | 169 ± 39 (1.4) | 3.0 | 373 ± 11 (1.0) | 350 ± 27 (1.0) |
C + | 720 ± 28b | 500 ± 32c | C + | 1375 ± 35d | 1387 ± 37c | C + | 1115 ± 25b | 1450 ± 70c | C + | 1468 ± 53e | 1403 ± 33f |
B. correifolia | |||||||||||
0.0 a | 20 ± 4 | 68 ± 1 | 0.0 a | 93 ± 6 | 114 ± 11 | 0.0 a | 172 ± 2 | 99 ± 1 | 0.0 a | 352 ± 30 | 435 ± 43 |
2.1 | 16 ± 3 (0.8) | 86 ± 6 (1.3) | 0.5 | 73 ± 3 (0.8) | 103 ± 5 (0.9) | 0.5 | 185 ± 6 (1.1) | 85 ± 4 (0.9) | 0.5 | 397 ± 11 (1.1) | 608 ± 45 (1.4) |
4.2 | 18 ± 2 (0.9) | 80 ± 3 (1.2) | 1.0 | 90 ± 10 (1.0) | 106 ± 8 (0.9) | 1.0 | 165 ± 11 (1.0) | 123 ± 11 (1.3) | 1.0 | 386 ± 33 (1.1) | 564 ± 35 (1.3) |
8.3 | 27 ± 3 (1.3) | 66 ± 6 (1.0) | 2.1 | 93 ± 8 (1.0) | 96 ± 9 (0.8) | 2.1 | 166 ± 18 (1.0) | 135 ± 4 (1.4) | 2.1 | 413 ± 16 (1.2) | 484 ± 33 (1.1) |
12.5 | 37 ± 10 (1.8) | 62 ± 3 (0.9) | 3.1 | 94 ± 11 (1.0) | 115 ± 12 (1.0) | 3.1 | 186 ± 5 (1.1) | 110 ± 4 (1.1) | 3.1 | 333 ± 50 (1.0) | 354 ± 38 (0.8) |
16.7 | 31 ± 6 (1.5) | 60 ± 9 (0.9) | 4.2 | 65 ± 6 (0.7) | 94 ± 4 (0.8) | 4.2 | 143 ± 10 (0.8) | 134 ± 5 (1.4) | 4.2 | 285 ± 21 (0.8) | 322 ± 32 (0.7) |
C + | 730 ± 28b | 500 ± 32c | C + | 1250 ± 35d | 700 ± 37c | C + | 950 ± 25b | 1450 ± 70c | C+ | 1468 ± 53e | 1403 ± 33f |
B. coccolobifolia | |||||||||||
0.0 a | 37 ± 8 | 24 ± 4 | 0.0 a | 112 ± 13 | 92 ± 9 | 0.0 a | 172 ± 2 | 123 ± 15 | 0.0 a | 406 ± 11 | 341 ± 34 |
2.0 | 56 ± 3* (1.5) | 56 ± 6**(2.3) | 0.5 | 115 ± 10 (1.0) | 102 ± 12 (1.1) | 0.5 | 129 ± 15 (0.7) | 144 ± 11 (1.2) | 0.5 | 345 ± 8 (0.9) | 386 ± 17 (1.1) |
4.0 | 61 ± 8* (1.7) | 51 ± 1**(2.1) | 1.0 | 135 ± 18 (1.2) | 115 ± 7 (1.3) | 1.0 | 145 ± 10 (0.8) | 163 ± 11 (1.3) | 1.0 | 338 ± 13 (0.8) | 366 ± 12 (1.1) |
8.0 | 70 ± 9* (1.9) | 67 ± 13*(2.8) | 2.1 | 154 ± 25 (1.4) | 110 ± 11 (1.2) | 2.1 | 175 ± 15 (1.0) | 208 ± 29* (1.7) | 2.1 | 350 ± 23 (0.9) | 330 ± 24 (1.0) |
12.0 | 102 ± 10**(2.8) | 64 ± 9**(2.6) | 3.1 | 170 ± 14 (1.5) | 108 ± 8 (1.2) | 3.1 | 214 ± 5 (1.2) | 215 ± 13**(1.8) | 3.1 | 355 ± 13 (0.9) | 297 ± 8 (0.9) |
16.0 | 67 ± 10* (1.9) | 63 ± 13*(2.6) | 4.2 | 143 ± 27 (1.3) | 115 ± 18 (1.3) | 4.2 | 190 ± 7 (1.1) | 237 ± 34* (1.9) | 4.2 | 358 ± 10 (0.9) | 261 ± 2 (0.8) |
C+ | 531 ± 28b | 500 ± 30c | C + | 1375 ± 35d | 700 ± 38c | C+ | 950 ± 25b | 700 ± 30c | C + | 1143 ± 28e | 1403 ± 33f |
B. ligustrifolia | |||||||||||
0.0 a | 18 ± 3 | 24 ± 4 | 0.0 a | 210 ± 33 | 87 ± 15 | 0.0 a | 110 ± 9 | 115 ± 1 | 0.0 a | 262 ± 25 | 407 ± 30 |
2.2 | 21 ± 1 (1.2) | 22 ± 5 (0.9) | 0.08 | 226 ± 13 (1.1) | 114 ± 13 (1.3) | 0.16 | 106 ± 5 (1.0) | 132 ± 12 (1.2) | 0.02 | 330 ± 16 (1.3) | 379 ± 45 (0.9) |
4.0 | 22 ± 1 (1.3) | 27 ± 8 (1.1) | 0.16 | 211 ± 12 (1.0) | 98 ± 6 (1.1) | 0.31 | 109 ± 8 (1.0) | 136 ± 8 (1.2) | 0.04 | 232 ± 2 (0.9) | 382 ± 21 (0.9) |
9.0 | 20 ± 2 (1.1) | 38 ± 7 (1.6) | 0.31 | 224 ± 37 (1.1) | 90 ± 9 (1.0) | 0.62 | 127 ± 7 (1.2) | 132 ± 19 (1.2) | 0.08 | 244 ± 25 (0.9) | 411 ± 20 (1.0) |
13.5 | 35 ± 6* (2.0) | 34 ± 9 (1.4) | 0.47 | 227 ± 24 (1.1) | 94 ± 3 (1.1) | 0.94 | 90 ± 6 (0.8) | 145 ± 17 (1.3) | 0.12 | 243 ± 22 (0.9) | 395 ± 12 (1.0) |
18.0 | 36 ± 5* (2.0) | 32 ± 2 (1.3) | 0.62 | 209 ± 11 (1.0) | 93 ± 16 (1.1) | 1.25 | 121 ± 1 (1.1) | 133 ± 4 (1.2) | 0.16 | 258 ± 11 (1.0) | 328 ± 15 (0.8) |
C + | 300 ± 12b | 227 ± 16c | C + | 919 ± 17d | 987 ± 32c | C + | 1110 ± 32b | 1036 ± 41c | C + | 1349 ± 45e | 1464 ± 43f |
B. fagifolia | |||||||||||
0.0 a | 23 ± 2 | 22 ± 3 | 0.0 a | 124 ± 10 | 100 ± 7 | 0.0 a | 154 ± 10 | 164 ± 23 | 0.0 a | 321 ± 39 | 300 ± 58 |
0.6 | 26 ± 1 (1.1) | 28 ± 4 (1.3) | 0.6 | 146 ± 13 (1.2) | 121 ± 9 (1.2) | 0.6 | 190 ± 16 (1.2) | 175 ± 21 (1.1) | 0.6 | 396 ± 38 (1.2) | 269 ± 67 (0.9) |
1.2 | 23 ± 3 (1.0) | 29 ± 2 (1.3) | 1.2 | 127 ± 5 (1.0) | 115 ± 3 (1.2) | 1.2 | 172 ± 7 (1.1) | 176 ± 25 (1.1) | 1.2 | 385 ± 31 (1.2) | 332 ± 23 (1.1) |
2.5 | 27 ± 2 (1.2) | 24 ± 8 (1.1) | 2.5 | 125 ± 18 (1.0) | 126 ± 9 (1.3) | 2.5 | 171 ± 16 (1.1) | 194 ± 11 (1.2) | 2.5 | 356 ± 25 (1.1) | 320 ± 54 (1.1) |
3.7 | 38 ± 8* (1.7) | 25 ± 2 (1.1) | 3.7 | 139 ± 23 (1.1) | 117 ± 24 (1.2) | 3.7 | 176 ± 12 (1.1) | 184 ± 6 (1.1) | 3.7 | 261 ± 47 (0.8) | 273 ± 69 (0.9) |
5.0 | 38 ± 6* (1.7) | 29 ± 4 (1.3) | 5.0 | 155 ± 5 (1.3) | 107 ± 10 (1.1) | 5.0 | 172 ± 11 (1.1) | 176 ± 20 (1.1) | 5.0 | 277 ± 64 (0.9) | 221 ± 43 (0.7) |
C+ | 947 ± 88b | 767 ± 115c | C+ | 1682 ± 98 d | 1956 ± 78c | C + | 1766 ± 49b | 1989 ± 89c | C + | 2656 ± 60e | 2932 ± 97f |
B. intermedia | |||||||||||
0.0 a | 22 ± 5 | 21 ± 8 | 0.0 a | 151 ± 14 | 151 ± 4 | 0.0 a | 176 ± 10 | 249 ± 22 | 0.0 a | 303 ± 99 | 396 ± 12 |
0.6 | 23 ± 3 (1.0) | 21 ± 7 (1.0) | 0.6 | 162 ± 7 (1.1) | 169 ± 12 (1.1) | 0.6 | 187 ± 25 (1.1) | 304 ± 28 (1.2) | 0.6 | 274 ± 36 (0.9) | 427 ± 66 (1.1) |
1.2 | 28 ± 4 (1.3) | 21 ± 3 (1.0) | 1.2 | 165 ± 5 (1.1) | 157 ± 15 (1.0) | 1.2 | 228 ± 16 (1.3) | 315 ± 7 (1.3) | 1.2 | 243 ± 19 (0.8) | 380 ± 28 (1.0) |
2.5 | 30 ± 3 (1.4) | 17 ± 6 (0.8) | 2.5 | 142 ± 10 (0.9) | 160 ± 5 (1.1) | 2.5 | 201 ± 26 (1.1) | 261 ± 18 (1.0) | 2.5 | 285 ± 64 (0.9) | 401 ± 60 (1.0) |
3.7 | 28 ± 1 (1.3) | 25 ± 8 (1.2) | 3.7 | 155 ± 18 (1.0) | 150 ± 4 (1.0) | 3.7 | 199 ± 7 (1.1) | 270 ± 19 (1.1) | 3.7 | 345 ± 61 (1.1) | 351 ± 63 (0.9) |
5.0 | 35 ± 5* (1.6) | 17 ± 2 (0.8) | 5.0 | 163 ± 8 (1.1) | 140 ± 7 (0.9) | 5.0 | 176 ± 23 (1.0) | 261 ± 13 (1.0) | 5.0 | 302 ± 53 (1.0) | 281 ± 72 (0.7) |
C + | 872 ± 67b | 736 ± 79c | C + | 1512 ± 64d | 1500 ± 88c | C+ | 1196 ± 52b | 1217 ± 69c | C+ | 2539 ± 187e | 2114 ± 162f |