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Table 2 Analgesic effect of crude methanol extract of A. sessilis aerial parts (MEAAS) in acetic acid-induced pain model mice

From: A preliminary evaluation of antihyperglycemic and analgesic activity of Alternanthera sessilis aerial parts

Treatment Dose (mg/kg body weight) Mean number of abdominal constrictions % inhibition
Control 10 ml 5.8 ± 0.37 -
Aspirin 200 mg 4.0 ± 0.84 31.0*
Aspirin 400 mg 2.8 ± 0.37 51.7*
(MEAAS) 50 mg 4.2 ± 0.49 27.6*
(MEAAS) 100 mg 3.6 ± 0.51 37.9*
(MEAAS) 200 mg 3.4 ± 0.40 41.4*
(MEAAS) 400 mg 3.2 ± 0.37 44.8*
  1. All administrations (aspirin and extract) were made orally. Values represented as mean ± SEM, (n = 5); *P < 0.05; significant compared to control.