Table 1 In vitro antimalarial activity of plumbagin, chloroquine and artesunate
From: Antimalarial activity of plumbagin in vitro and in animal models
Compound | IC50against 3D7 chloroquine-sensitive P. falciparum clones (nM) | IC50against K1 chloroquine resistant P. falciparum clones (nM) |
|---|---|---|
Plumbagin | 580 (270–640) | 370 (270–490) |
Chloroquine | 10.5 (9.4–12.1) | 128.7 (109.3–139.2) |
Artesunate | 2.1 (1.98–2.54) | 1.91 (16.1–2.1) |