Body weights and blood glucose levels at different weeks. The bar graphs summarize average values for body weight and blood glucose. Body weights gradually increased in the model group mice, which indicated that astragalus treatment could significantly inhibit a gain in body weight (A). Diabetic mice (MG) remained hyperglycemic and C57BL/6J mice (CG) remained normoglycemic throughout the period of study. The tendency for astragalus treatment to reduce the blood glucose concentration in diabetic mice was apparent. However, blood glucose levels did not return to normal following the administration of astragalus (B). Data presented are means ± SD (n = 6–8). CG = the control group, MG = the model group, and TG = the astragalus treatment group. Compared with NG, *P < 0.05, **P < 0.01. Compared with MG, Δ
P < 0.05, ΔΔ
P < 0.01.