Table 5 Neurotransmitter levels and their metabolites (ng/g) after acute oral treatment with C . aurantium EO (5 mg/kg)
Structures and treatments | ||||||||
|---|---|---|---|---|---|---|---|---|
Cortex | Striatum | Pons | Hypothalamus | |||||
TW | EO | TW | EO | TW | EO | TW | EO | |
DA | 845.6 ± 239.9 (10) | 895.6 ± 321.3 (7) | 8324.3 ± 517.1 (11) | 8331.2 ± 1040.1 (7) | 15.2 ± 3.8 (10) | 18.6 ± 6.2 (7) | 53.1 ± 3.8 (10) | 58.3 ± 5.8 (6) |
DOPAC | 94.6 ± 15.9 (12) | 85.6 ± 17.4 (8) | 437.4 ± 44.5 (11) | 415.5 ± 49.9 (7) | 11.6 ± 1.6 (11) | 8.4 ± 1.1 (8) | 58.6 ± 5.6 (12) | 64.2 ± 4.7 (8) |
HVA | 427.3 ± 80.4 (12) | 567.8 ± 112.5 (8) | 1121.9 ± 96.8 (11) | 1384.9 ± 193.5 (7) | 317.2 ± 87.9 (11) | 388.3 ± 141.3 (8) | 236.2 ± 36.8 (12) | 388.8 ± 74.5 (8) |
5HT | 1246.9 ± 85.8 (12) | 1270.1 ± 81.0 (8) | 1686.3 ± 102.4 (11) | 1665.9 ± 170.9 (7) | 2782.4 ± 259.8 (11) | 2075.4 ± 309.9 (8) | 1660.1 ± 126.2 (12) | 1599.2 ± 113.9 (8) |
5HIAA | 192.7 ± 17.5 (12) | 229.3 ± 33.7 (8) | 317.1 ± 30.9 (11) | 320.3 ± 40.0 (7) | 879.2 ± 69.5 (10) | 644.1 ± 76.4 (7) | 341.7 ± 20.9 (12) | 310.9 ± 19.4 (8) |