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Table 5 Neurotransmitter levels and their metabolites (ng/g) after acute oral treatment with C . aurantium EO (5 mg/kg)

From: Citrus aurantium L. essential oil exhibits anxiolytic-like activity mediated by 5-HT1A-receptors and reduces cholesterol after repeated oral treatment

Structures and treatments
  Cortex Striatum Pons Hypothalamus
  TW EO TW EO TW EO TW EO
DA 845.6 ± 239.9 (10) 895.6 ± 321.3 (7) 8324.3 ± 517.1 (11) 8331.2 ± 1040.1 (7) 15.2 ± 3.8 (10) 18.6 ± 6.2 (7) 53.1 ± 3.8 (10) 58.3 ± 5.8 (6)
DOPAC 94.6 ± 15.9 (12) 85.6 ± 17.4 (8) 437.4 ± 44.5 (11) 415.5 ± 49.9 (7) 11.6 ± 1.6 (11) 8.4 ± 1.1 (8) 58.6 ± 5.6 (12) 64.2 ± 4.7 (8)
HVA 427.3 ± 80.4 (12) 567.8 ± 112.5 (8) 1121.9 ± 96.8 (11) 1384.9 ± 193.5 (7) 317.2 ± 87.9 (11) 388.3 ± 141.3 (8) 236.2 ± 36.8 (12) 388.8 ± 74.5 (8)
5HT 1246.9 ± 85.8 (12) 1270.1 ± 81.0 (8) 1686.3 ± 102.4 (11) 1665.9 ± 170.9 (7) 2782.4 ± 259.8 (11) 2075.4 ± 309.9 (8) 1660.1 ± 126.2 (12) 1599.2 ± 113.9 (8)
5HIAA 192.7 ± 17.5 (12) 229.3 ± 33.7 (8) 317.1 ± 30.9 (11) 320.3 ± 40.0 (7) 879.2 ± 69.5 (10) 644.1 ± 76.4 (7) 341.7 ± 20.9 (12) 310.9 ± 19.4 (8)
  1. TW (tween). The data are presented as the mean ± SEM. Any differences were compared with an unpaired t-test. The number of animals is different for each group because some structures could not be evaluated due to technical reasons.