Curcumin regulates gene expression of insulin like growth factor, B-cell CLL/lymphoma 2 and antioxidant enzymes in streptozotocin induced diabetic rats

Table 2 Effect of oral administration of curcumin at the start and during six weeks of the experiment on blood glucose concentration (mg/dl) in streptozotocin diabetic rats

Groups	Blood glucose concentration (mg/dl)
Groups	At the start	1^stweek	2^ndweek	4^thweek	6^thweek
I	100 ± 1.1	100 ± 2.1	96 ± 1.2	92 ± 1.1	90 ± 2.1
II	102 ± 1.2	366 ± 1.9*	330 ± 1.5*	340 ± 1.4*	350 ± 1.7*
III	98.2 ± 2.1	199 ± 1.1**	187 ± 1.0**	192 ± 1.3**	197 ± 1.2**

I (non diabetic), II (diabetic), III (diabetic treated with curcumin); Values are mean ± SD of 8 rats; *Mean values are significantly (P < 0.05) different compare to the control (group I). **Mean values are significantly (P < 0.05) different compare to diabetic rats (group II).