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Table 2 Evaluation of antiproliferative effects of marine bacterial extracts on various cancer cell lines

From: Induction of apoptosis in cancer cell lines by the Red Sea brine pool bacterial extracts

Strain HeLa MCF-7 DU145
200 μg/mL 500 μg/mL 200 μg/mL 500 μg/mL 200 μg/mL 500 μg/mL
P1-16A 8.0 16.2 0 0 3.2 1.0
P3-16A 12.9 32.8 0 0 4.9 6.1
P5-86B 2.8 2.8 0 0 0.8 8.3
H102 54.6 37.0 21.7 18.0 3.0 2.0
P3-16B 0 0 0 0 11.7 14.4
P6-86 0 0 0 0 2.0 6.8
P2-16A 0 0 0 0 7.3 6.0
P1-26A 0 0 0 0 3.9 2.7
P5-86A 0 0 0 0 1.4 10.2
P3-86B(2) 0 95.2 0 0 4.5 7.2
P3-86A 31.9 39.8 32.1 35.3 2.3 3.0
P1-5 27.2 56.3 33.4 54.0 52.1 59.9
P1-16C 30.7 35.3 33.5 51.1 41.4 47.0
H105 17.1 19.0 16.3 23.4 7.4 7.5
P3-37A 1.1 13.6 16.4 28.5 24.3 28.8
K2 1.4 15.5 13.2 12.4 14.6 11.9
P4-13A 0 6.9 4.2 3.8 0 12.3
P3-37C 0 4.9 22.1 34.8 21.7 1.5
K18 16.0 36.6 11.6 37.0 24.1 45.3
P3-37B 12.3 43.6 32.5 89.8 41.8 34.6
K30 24.7 28.4 27.9 88.2 18.6 30.4
P2-13B 35.3 50.5 39.5 51.4 62.5 60.7
P4-13B 8.2 8.4 29.0 37.7 44.7 39.8
  1. The growth of cells was inhibited in a dose-dependent manner at concentrations of 200 and 500 μg/mL after 48 h. MTT assay was used to assess the growth inhibitory potential of extracts and is presented as percent growth inhibition relative to untreated cells. The Z-factor for this experiment was calculated to be 0.76. The extracts selected for apoptosis analysis are presented in bold letters.