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Table 2 MIC 100 (ÎŒg/mL) of the natural products against Trichophyton rubrum

From: Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte Trichophyton rubrum

Strain

CRL

FLC

QCT

GEN

EAC

LUT

GAL

T-CHL

MYA3108

125

63

125

>1000

>1000

250

>1000

7.5

ΔTruMDR2

15

30

63

>1000

>1000

63

>1000

1.9

  1. CRL: cerulenin; EAC: ellagic acid; FLC: fluconazole; GAL: galangin; GEN: genistein; QCT: quercetin; LUT: luteolin; T-CHL: trans-chalcone.