Herbal-drug interaction induced rhabdomyolysis in a liposarcoma patient receiving trabectedin

Table 2 An overview of the most common herbal medicines involved in pharmacokinetic CYP interactions with chemotherapeutic drugs

Herb	Indication	CYP involvment	Effect on metabolism	Reference
Ginko biloba	Psychostimulant	2 D6	inhibition	[12]
Ginko biloba	Psychostimulant	3 A4	inhibition	[12]
Aloe vera	Antioxidant	3 A	inhibition	[13]
	Antiproliferative	3 A
	Immunostimulant	2C9
Green tea	Immunostimulant	3 A	inhibition	[14]
Saint John’s Wort	Antidepressant	3 A4	inhibition	[15]
		2 C9
		1 A2
		1 B1
		2 D6
Ginseng	Psychostimulant	3 A	inhibition	[16]
	Psychostimulant	2 C9
	Immunostimulant	2 C19
	Immunostimulant	2 d6
Echinacea	Immunostimulant	3 A	inhibition	[17]
Echinacea	Immunostimulant	2 D6	inhibition	[17]
Garlic	Antioxidant	3 A	inhibition	[18]
	Immunostimulant	2 C9
	Antiplatelet activity	2 C19

ISSN: 2662-7671