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Table 1 Susceptibility of Trichomonas vaginalis to water-ethanol (WE) and butanolic (BE) extracts, and saponins (SP) of Sapindus saponaria

From: Spermicidal and anti-Trichomonas vaginalis activity of Brazilian Sapindus saponaria

Concentration (mg/mL)

Viable trophozoites/mL

Viable trophozoites/mL

CS strain

ATCC strain

WE

BE

SP

WE

BE

SP

0.156

--

--

--

7.5 × 103

--

--

0.078

2.5 × 103

1.0 × 104

--

1.5 × 104

1.0 × 104

--

0.039

2.5 × 103

2.5 × 104

1.5 × 104

1.25 × 104

1.75 × 104

1.25 × 104

0.019

2.5 × 103

5.0 × 103

1.0 × 104

6.25 × 104

2.5 × 104

1.0 × 104

C+

1.5 × 104

1.25 × 104

1.5 × 104

5.25 × 104

7.5 × 103

5.5 × 104

C–

--

--

--

--

--

--

  1. Not found viable trophozoites in concentrations at 0.312 to 10.0 (mg/mL) for extracts or SP.
  2. -- not found viable trophozoites.
  3. C+ positive control - tube without addition of extracts or SP.
  4. C– negative control - tube without addition of trophozoites.