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Table 2 Body weight of Wistar rats obtained after 30 consecutive days of treatment with Dioscorea villosa dry extract (DV) 1000 mg/kg given by oral route

From: Bioassay-guided evaluation of Dioscorea villosa – an acute and subchronic toxicity, antinociceptive and anti-inflammatory approach

  

Control

DV 1000 mg/kg

Gender

Day

Body weight (g)

Increase (%)

Body weight (g)

Increase (%)

Male

0

352.6 ± 4.5

0.00

278.8 ± 5.1

0.00

 

10

350.3 ± 4.4

−0.65

293.13 ± 4.9***

5.14

 

20

362.2 ± 4.5

2.72

305.00 ± 3.9***

9.40

 

30

364.0 ± 4.0

3.23

310.15 ± 4.2***

11.24

Female

0

195.1 ± 2.6

0.00

159.0 ± 3.5

0.00

 

10

200.4 ± 3.5

2.72

176.0 ± 3.1*

10.69

 

20

204.9 ± 3.1

5.02

189.7 ± 2.5***

19.30

 

30

214.9 ± 4.2

10.15

196.4 ± 3.1***

23.50

  1. Values are expressed as mean ± S.E.M. (n = 10 animals/group). * Significant difference from control group (*p < 0.05; **p < 0.01; ***p < 0.001 by ANOVA, followed by Tukey test).