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Table 3 Differential protein levels in Phyllanthus -treated dengue-infected Vero cells

From: Effects of cocktail of four local Malaysian medicinal plants (Phyllanthus spp.) against dengue virus 2

ID Accession Score Possible proteins C C + P C + V C + V + P
Viral Entry
3 Q28222.1 1059 Heat Shock Protein 70 (Hsp70) 192.1 200.2 312.2 234.3
4 Q28222.1 768 Heat Shock Protein 70 (Hsp 70) 199.5 287.4 419.3 282.2
5 Q2IBA6.1 483 Hepatocyte Growth Factor Receptor (HGFR) 192.7 200.4 313.4 259.7
12 Q2IBA6.1 136 Hepatocyte Growth Factor Receptor (HGFR) 222.5 0.0 313.2 218.2
14 Q2IBA6.1 178 Hepatocyte Growth Factor Receptor (HGFR) 206.3 0.0 312.5 200.1
22 Q2IBA6.1 139 Hepatocyte Growth Factor Receptor (HGFR) 231.9 237.1 331.3 225.5
39 Q2IBA6.1 132 Hepatocyte Growth Factor Receptor (HGFR) 203.8 206.7 390.0 212.9
41 Q2IBA6.1 120 Hepatocyte Growth Factor Receptor (HGFR) 211.0 224.2 333.2 221.6
Viral Uncoating
37 AAT48107.1 132 Trim 1 187.4 198.8 366.1 535.3
Viral Transcription and Translation
7 ABB92440.1 489 RNA Binding Motif 1 (RBMI) 197.6 0.0 412.3 222.2
8 ABB92440.1 383 RNA Binding Motif 1 (RBMI) 206.0 0.0 362.1 226.7
10 ABB92440.1 141 RNA Binding Motif 1 (RBMI) 213.8 0.0 372.7 221.2
24 ABB92440.1 77 RNA Binding Motif 1 (RBMI) 180.4 0.0 362.4 181.7
42 ABB92440.1 633 RNA Binding Motif 1 (RBMI) 202.9 222.2 424.2 313.3
27 NP_739587.2 173 Nonstructural protein NS3 0.0 0.0 312.3 123.2
35 2FOM_B 151 Chain B, Dengue virus NS2bNS3 Protease 0.0 0.0 262.8 123.2
38 Q7YR26.1 63 DNA topoisomerase 1 (DNA Topo 1) 202.9 211.3 373.2 229.2
43 Q5XXB5.1 84 DNA mismatch repair protein Msh2 201.1 212.2 415.2 311.3
44 Q5XXB5.1 129 DNA mismatch repair protein Msh2 209.1 205.3 394.2 213.3
47 Q5RF69 185 Histidine triad nucleotide-binding protein 1 194.4 189.1 393.4 194.0
Viral Post-translational Modification
25 Q4VIT5.1 346 Calreticulin 188.0 200.4 333.3 213.2
Glucose Uptake and Glycolytic Enzymes
6 Q8CGV6 559 Glyceraldehyde-3-phosphate dehydrogenase (G3PD) 213.9 231.3 524.1 313.2
49 AAF17105.1 151 Polysialyltransferase 207.1 212.3 313.7 232.3
Cytoskeletal assembly
1 Q76N69.1 846 Beta actin 168.8 185.3 512.2 273.2
  1. C = cells only; C + P = Phyllanthus-treated cells; C + V = dengue-infected cells; C + P + V = Phyllanthus treated dengue infected cells.