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Table 3 The R max and pIC 50 values of F1 in aortic rings pretreated with various drugs

From: Potassium channel openers and prostacyclin play a crucial role in mediating the vasorelaxant activity of Gynura procumbens

Drugs

Rmax(%)

pIC50

Control

98.39 ± 5.79

2.62 ± 0.09

TEA

97.61 ± 24.04

2.58 ± 0.30

Glibenclamide

73.23 ± 4.84*

2.19 ± 0.06*

4-aminopyridine

74.31 ± 6.89*

2.08 ± 0.05*

L-NAME

82.77 ± 13.12

2.49 ± 0.12

Indomethacin

68.15 ± 5.96*

2.37 ± 0.05*

ODQ

88.46 ± 6.49

2.51 ± 0.14

Methylene blue

107.98 ± 9.29

2.85 ± 0.17

Atropine

92.12 ± 2.64

2.53 ± 0.07

Propanolol

93.02 ± 8.93

2.46 ± 0.09

  1. Values are means ± S.E.M (n = 6), *P < 0.05 compared with control (without any drugs).