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Table 4 Effect of sub-chronic (28 days) administration of aqueous extract of Terminalia paniculata on plasma urea, creatinine and hepatic enzyme levels in Swiss albino mice

From: Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl4-induced liver injury in rodents

Groups Urea (mg/dl) Creatinine (mg/dl) ACP (U/L) ALP (U/L) AST (U/L) ALT (U/L)
NC 9.23 ± 0.85 0.97 ± 0.05 23.48 ± 1.57 12.75 ± 1.04 45.21 ± 2.10 27.66 ± 2.54
TPW 750 9.47 ± 0.93ns 0.89 ± 0.03ns 22.95 ± 1.21ns 12.40 ± 1.10ns 43.89 ± 1.86ns 26.90 ± 2.92ns
TPW 1500 9.70 ± 0.96ns 0.94 ± 0.04ns 23.28 ± 1.50ns 12.89 ± 0.86ns 42.09 ± 2.46ns 28.48 ± 2.73ns
TPW 3000 9.89 ± 1.01ns 1.02 ± 0.06ns 23.84 ± 1.33ns 13.02 ± 0.90ns 44.27 ± 1.78ns 27.36 ± 2.66ns
  1. TPW aqueous extract of Terminalia paniculata, NC normal control, ACP acid phosphatase, ALP alkaline phosphatase, AST aspartate aminotransferase, ALT alanine aminotransferase.
  2. ns no significance between TPW versus NC.