Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl 4 -induced liver injury in rodents

Table 4 Effect of sub-chronic (28 days) administration of aqueous extract of Terminalia paniculata on plasma urea, creatinine and hepatic enzyme levels in Swiss albino mice

Groups	Urea (mg/dl)	Creatinine (mg/dl)	ACP (U/L)	ALP (U/L)	AST (U/L)	ALT (U/L)
NC	9.23 ± 0.85	0.97 ± 0.05	23.48 ± 1.57	12.75 ± 1.04	45.21 ± 2.10	27.66 ± 2.54
TPW 750	9.47 ± 0.93^ns	0.89 ± 0.03^ns	22.95 ± 1.21^ns	12.40 ± 1.10^ns	43.89 ± 1.86^ns	26.90 ± 2.92^ns
TPW 1500	9.70 ± 0.96^ns	0.94 ± 0.04^ns	23.28 ± 1.50^ns	12.89 ± 0.86^ns	42.09 ± 2.46^ns	28.48 ± 2.73^ns
TPW 3000	9.89 ± 1.01^ns	1.02 ± 0.06^ns	23.84 ± 1.33^ns	13.02 ± 0.90^ns	44.27 ± 1.78^ns	27.36 ± 2.66^ns

TPW aqueous extract of Terminalia paniculata, NC normal control, ACP acid phosphatase, ALP alkaline phosphatase, AST aspartate aminotransferase, ALT alanine aminotransferase.
ns no significance between TPW versus NC.

ISSN: 2662-7671