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Table 4 Effect of sub-chronic (28 days) administration of aqueous extract of Terminalia paniculata on plasma urea, creatinine and hepatic enzyme levels in Swiss albino mice

From: Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl4-induced liver injury in rodents

Groups

Urea (mg/dl)

Creatinine (mg/dl)

ACP (U/L)

ALP (U/L)

AST (U/L)

ALT (U/L)

NC

9.23 ± 0.85

0.97 ± 0.05

23.48 ± 1.57

12.75 ± 1.04

45.21 ± 2.10

27.66 ± 2.54

TPW 750

9.47 ± 0.93ns

0.89 ± 0.03ns

22.95 ± 1.21ns

12.40 ± 1.10ns

43.89 ± 1.86ns

26.90 ± 2.92ns

TPW 1500

9.70 ± 0.96ns

0.94 ± 0.04ns

23.28 ± 1.50ns

12.89 ± 0.86ns

42.09 ± 2.46ns

28.48 ± 2.73ns

TPW 3000

9.89 ± 1.01ns

1.02 ± 0.06ns

23.84 ± 1.33ns

13.02 ± 0.90ns

44.27 ± 1.78ns

27.36 ± 2.66ns

  1. TPW aqueous extract of Terminalia paniculata, NC normal control, ACP acid phosphatase, ALP alkaline phosphatase, AST aspartate aminotransferase, ALT alanine aminotransferase.
  2. ns no significance between TPW versus NC.