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Table 2 Identification results of metabolites in this study

From: Urine metabolic profile changes of CCl4-liver fibrosis in rats and intervention effects of Yi Guan Jian Decoction using metabonomic approach

Metabolites Model group vs control group YGJD group vs model group YGJD group vs control group Pathways
Indole-3-carboxylic acid ↑* NS Tryptophan metabolism
Butanedioic acid ↑* ↓# NS Energy metabolism
Glycine ↓* NS P450 metabolism
Leucine ↓* NS Amino acid metabolism
Phenol ↓* NS Flora metabolism
Proline ↓** ↑# NS Amino acid metabolism
Citrate ↑* ↓## NS Energy metabolism
Hippuric acid ↑* ↓# NS P450 metabolism
Glutamate ↑* NS Amino acid metabolism
Hexadecanoic acid ↑* ↓# NS Fatty acid metabolism
Oleic acid ↓* NS Fatty acid metabolism
Octadecenoic acid ↓* Fatty acid metabolism
Lysine ↓** Amino acid metabolism
Tryptophan ↓* ↑# NS Tryptophan metabolism
  1. “↓” indicates relative decrease, “↑” indicates relative increase, *P < 0.05, ** P < 0.01 compared with control group; ## P < 0.01, # P < 0.05 compared with model group; P < 0.05 compared with control group; NS indicates Non-significant. Results were expressed as x ¯ + / SE , units were mg/mL urine sample, which are provided in the Additional file 1.