|
Metabolites
|
Model group vs control group
|
YGJD group vs model group
|
YGJD group vs control group
|
Pathways
|
|---|
|
Indole-3-carboxylic acid
|
↑*
|
↓
|
NS
|
Tryptophan metabolism
|
|
Butanedioic acid
|
↑*
|
↓#
|
NS
|
Energy metabolism
|
|
Glycine
|
↓*
|
↑
|
NS
|
P450 metabolism
|
|
Leucine
|
↓*
|
↑
|
NS
|
Amino acid metabolism
|
|
Phenol
|
↓*
|
↑
|
NS
|
Flora metabolism
|
|
Proline
|
↓**
|
↑#
|
NS
|
Amino acid metabolism
|
|
Citrate
|
↑*
|
↓##
|
NS
|
Energy metabolism
|
|
Hippuric acid
|
↑*
|
↓#
|
NS
|
P450 metabolism
|
|
Glutamate
|
↑*
|
↓
|
NS
|
Amino acid metabolism
|
|
Hexadecanoic acid
|
↑*
|
↓#
|
NS
|
Fatty acid metabolism
|
|
Oleic acid
|
↓*
|
↑
|
NS
|
Fatty acid metabolism
|
|
Octadecenoic acid
|
↓*
|
↑
| △ |
Fatty acid metabolism
|
|
Lysine
|
↓**
|
↑
| △ |
Amino acid metabolism
|
|
Tryptophan
|
↓*
|
↑#
|
NS
|
Tryptophan metabolism
|
- “↓” indicates relative decrease, “↑” indicates relative increase, *P < 0.05, ** P < 0.01 compared with control group; ## P < 0.01, # P < 0.05 compared with model group; △P < 0.05 compared with control group; NS indicates Non-significant. Results were expressed as , units were mg/mL urine sample, which are provided in the Additional file 1.
