From: Chinese herbal medicine for impaired glucose tolerance: a randomized placebo controlled trial
Parameter | Jiangtang Xiaozhi | Placebo | P | ||
---|---|---|---|---|---|
Baseline | Week 16 | Baseline | Week 16 | ||
Fasting blood glucose (mmol/L) | 6.3 ± 0.9 | 6.3 ± 1.1 | 6.7 ± 1.0 | 6.7 ± 1.3 | 0.70 |
Postprandial blood glucose (mmol/L) | 10.45 ± 2.3 | 9.66 ± 2.6* | 10.98 ± 2.9 | 10.60 ± 3.4 | 0.51 |
HbA1c (%) | 6.4 ± 0.7 | 6.5 ± 0.7 | 6.3 ± 0.6 | 6.4 ± 0.6 | 0.62 |
Insulin (mmol/L) | 11.8 ± 6.9 | 11.6 ± 5.5 | 15.5 ± 9.7 | 22.1 ± 25.9 | 0.04 |
HOMA-IR | 1.63 ± 0.91 | 1.58 ± 0.74 | 2.06 ± 1.28 | 2.43 ± 1.59 | 0.06 |
HOMA%B | 81.52 ± 34.5 | 83.5 ± 38.1 | 86.51 ± 36.78 | 98.83 ± 48.29 | 0.26 |
HOMA%S | 81.84 ± 48.12 | 79.72 ± 44.14 | 72.78 ± 46.42 | 62.67 ± 38.48 | 0.34 |
Total cholesterol (mmol/L) | 4.91 ± 1.03 | 4.96 ± 0.94 | 4.47 ± 0.85 | 4.56 ± 0.81 | 0.46 |
HDL cholesterol (mmol/L) | 1.45 ± 0.44 | 1.54 ± 0.53 | 1.28 ± 0.30 | 1.24 ± 0.30 | 0.03 |
Triglycerides (mmol/L) | 1.6 ± 0.64 | 1.6 ± 0.76 | 1.67 ± 0.93 | 1.59 ± 0.86 | 0.92 |
C-reactive protein (mg/L) | 6.7 ± 7.6 | 4.66 ± 1.77 | 6.73 ± 5.25 | 5.18 ± 3.0 | 0.36 |
Weight (kg) | 80.5 ± 15.1 | 80.4 ± 15.0 | 92.0 ± 28.5 | 91.8 ± 28.6 | 0.84 |
BMI (kg/m2) | 29.8 ± 4.9 | 31.0 ± 1.8 | 32.0 ± 8.0 | 31.2 ± 1.8 | 0.64 |
Waist (cm) | 97.6 ± 11.1 | 98.6 ± 12.4 | 109.9 ± 22.1 | 106.3 ± 18.6 | 0.05 |
Systolic blood pressure (mmHg) | 124.5 ± 13.3 | 124.1 ± 15.5 | 134.4 ± 14.0 | 130.1 ± 16.1 | 0.96 |
Diastolic blood pressure (mmHg) | 76.4 ± 11.1 | 71.7 ± 8.6 | 81.7 ± 74.3 | 74.3 ± 2.2 | 0.96 |