In this group of practitioners, yogic breathing was characterized by a mean respiratory rate of 4.32 ± 1.87 breaths/min, mean minute ventilation of 6.09 ± 4.17 L/min, and mean end-tidal CO2 of 39.98 ± 7.07 mmHg compared with a mean respiratory rate of 15.0 ± .60 breaths/min, minute ventilation of 8.66 ± 2.25 L/min, and mean end-tidal CO2 of 32.68 ± 5.22 mmHg during paced breathing. The strength of the relationship (coherence) between respiration and heart period and respiration and systolic blood pressure did not differ between breathing patterns (p=0.74 and p=0.14). However, we found increased gain between respiration and heart period fluctuations (400.00 ± 154.19 msec/L vs 36.65 ± 10.32 mmHg/L, p=0.02) and between respiration and systolic blood pressure fluctuations (15.97 ± 9.32 msec/L vs 1.68 ± 0.68 mmHg/L, p=0.02) during yogic breathing compared with paced breathing.