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OA03.03. The effect of acupuncture on post cancer fatigue and wellbeing for women recovering from breast cancer: a feasibility randomized control trial


Persistent and severe fatigue following breast cancer treatment is estimated to affect over a third of breast cancer patients. To date the evidence of effectiveness for the management of fatigue using acupuncture is unclear. We undertook a study to examine the feasibility and effect of acupuncture with managing fatigue in breast cancer survivors.


We conducted a randomised controlled trial, comparing acupuncture with a placebo and a wait list control. Inclusion criteria included: aged between 18 and 70 years, a diagnosis of breast cancer, a score of >4 on the Brief Fatigue Inventory (BFI), and completed chemotherapy at least one month previously. Acupuncture was based on Traditional Chinese Medicine using a semi standardised treatment. The placebo control received non invasive needles using the Park Sham device, and placed away from points and meridians. Treatment was administered twice weekly over three weeks and weekly for three weeks. Endpoints were assessed at 2, 4 and 6 weeks, and included the BFI, Well-Being and Measure Yourself Concerns and Wellbeing questionnaire. In depth interviews were also conducted with women receiving acupuncture, exploring their sense of wellbeing, levels of fatigue and experience of acupuncture.


Thirty women were randomised and outcome data was available from 29 participants. At two weeks there was a significant reduction in fatigue for women receiving acupuncture compared to the placebo and wait list control (MD 5.3, 95% 4.5, 6.2, p=0.05). A trend to reduced fatigue for the acupuncture group was seen at week 4 (MD 4.6, 95% 3.6, 5.6, p=0.06), and at six weeks acupuncture demonstrated improved wellbeing (MD 2.7, 95% CI 2.2-3.2, p=0.006). Interviews demonstrated participants valued the therapeutic relationship, empowerment through self care and the invigorating nature of the intervention.


The study demonstrated acceptability, feasibility and encouraging results to plan further research.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Smith, C., Ussher, J., Perz, J. et al. OA03.03. The effect of acupuncture on post cancer fatigue and wellbeing for women recovering from breast cancer: a feasibility randomized control trial. BMC Complement Altern Med 12 (Suppl 1), O11 (2012).

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  • Breast Cancer
  • Cancer Survivor
  • Traditional Chinese Medicine
  • Breast Cancer Survivor
  • Therapeutic Relationship