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Table 3 MDR1 mRNA expression in H22/ADM cells at different times (24 h, 48 h, 72 h) (n = 6)

From: Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro

Group

2-▽▽Ct (Mean ± SD)

 

24 h

48 h

72 h

RFP 10 μmol/L

1.670 ± 0.027

1.977 ± 0.064

2.726 ± 0.086

H22/ADM

1.525 ± 0.039

1.797 ± 0.108

2.563 ± 0.048

VER 10 μmol/L

0.519 ± 0.045★

0.497 ± 0.107▴

0.440 ± 0.114●

APS 500 mg/L

0.616 ± 0.035★

0.565 ± 0.033▴

0.496 ± 0.072●

APS 100 mg/L

0.792 ± 0.163★

0.742 ± 0.077▴

0.898 ± 0.042●

APS 20 mg/L

0.890 ± 0.055★

1.067 ± 0.107▴

1.076 ± 0.108●

APS 4 mg/L

1.128 ± 0.051★

1.183 ± 0.058▴

1.412 ± 0.027●

APS 0.8 mg/L

1.260 ± 0.113★

1.406 ± 0.024▴

1.736 ± 0.063●

  1. ★ P < 0.05, vs. H22/ADM group (24 h); ▴ P < 0.05, vs. H22/ADM group (48 h);● P < 0.05, vs. H22/ADM group (72 h).
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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