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Table 1 Impact of APS on H22/ADM cell proliferation (n = 6)

From: Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitro

Agents

Concentration (mg/L)

OD Value (mean ± SD)

Inhibition Rate (%)

IC50 (mg/L)

IC50 95%CI (mg/L)

APS

0.8

0.71 ± 0.15

1.11

  
 

4

0.67 ± 0.12

6.69

  
 

20

0.61 ± 0.09

15.04

251.77

1.6 × 10–1.2 × 103

 

100

0.47 ± 0.04

34.54

  
 

500

0.27 ± 0.14

62.40

  

DDP

0.1

0.29 ± 0.02

59.61

  
 

1.0

0.21 ± 0.04

70.75

0.04

1.7 × 10-3–0.74

 

10

0.06 ± 0.03

91.64

  

NS

 

1.018 ± 1.06

ND

  

DMSO

0.1

0.918 ± 0.134

ND

  
  1. P < 0.05, vs. DDP; ND: Not calculated; SD: Standard deviation; NS: normal saline.