Treatment | % increase in body weight | Absolute liver weight (g) | Relative liver weight (% to body weight) | AgNORs (NORs/cell) | %DNA fragmentation |
---|---|---|---|---|---|
Control | 35.00 ± 0.87++ | 7.0 ± 0.23++ | 0.07 ± 0.002++ | 2.0 ± 0.33++ | 5.33 ± 2.46++ |
3 ml/kg CCl4 | 24.52 ± 0.92** | 8.6 ± .89** | 0.86 ± .0016** | 6.4 ± .29** | 22.50 ± 3.68** |
100 mg/kg SAME + CCl4 | 30.08 ± 0.81**++ | 7.4 ± 0.10*++ | 0.074 ± 0.001*++ | 3.5 ± 0.18**++ | 6.67 ± 2.08++ |
200 mg/kg SAME + CCl4 | 35.64 ± 0.73++ | 7.04 ± 0.23++ | 0.070 ± 0.0023++ | 2.14 ± 0.23++ | 5.67 ± 3.12++ |
100 mg/kg Silymarin + CCl4 | 36.82 ± 0.69++ | 6.83 ± 0.07++ | 0.068 ± 0.007++ | 1.9 ± 0.17**++ | 4.67 ± 2.23++ |
200 mg/kg SAME alone | 35.72 ± 0.70++ | 6.8 ± 0.12++ | 0.068 ± 0.011++ | 1.96 ± 0.12++ | 5.50 ± 3.2++ |