From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Main Study | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Liver | Kidney | Lungs | Heart | Testes | Spleen | Pancreas | Brain | Ovaries | ||
Distilled water | (10 ml/kg) | 2.84 ± 0.05 | 0.57 ± 0.02 | 0.77 ± 0.04 | 0.37 ± 0.03 | 1.52 ± 0.08 | 0.37 ± 0.03 | 0.28 ± 0.02 | 0.63 ± 0.03 | 0.08 ± 0.00 |
DAS-77 | 80 | 2.80 ± 0.19 | 0.64 ± 0.04 | 0.78 ± 0.05 | 0.34 ± 0.02 | 1.78 ± 0.29 | 0.32 ± 0.04 | 0.34 ± 0.03 | 0.70 ± 0.02 | 0.10 ± 0.00 |
DAS-77 | 400 | 2.66 ± 0.09 | 0.71 ± 0.03 | 0.88 ± 0.04 | 0.33 ± 0.02 | 1.99 ± 0.08 | 0.31 ± 0.02 | 0.42 ± 0.02 | 0.74 ± 0.08 | 0.14 ± 0.02** |
DAS-77 | 2000 | 2.41 ± 0.1* | 0.65 ± 0.06 | 0.78 ± 0.07 | 0.35 ± 0.02 | 1.91 ± 0.13 | 0.30 ± 0.02 | 0.32 ± 0.03 | 0.73 ± 0.01 | 0.14 ± 0.01* |