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Table 3 Effect of DAS-77 on weight of vital organs (per 100 g body weight) in the main study

From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats

Treatment Dose (mg/kg) Main Study
   Liver Kidney Lungs Heart Testes Spleen Pancreas Brain Ovaries
Distilled water (10 ml/kg) 2.84 ± 0.05 0.57 ± 0.02 0.77 ± 0.04 0.37 ± 0.03 1.52 ± 0.08 0.37 ± 0.03 0.28 ± 0.02 0.63 ± 0.03 0.08 ± 0.00
DAS-77 80 2.80 ± 0.19 0.64 ± 0.04 0.78 ± 0.05 0.34 ± 0.02 1.78 ± 0.29 0.32 ± 0.04 0.34 ± 0.03 0.70 ± 0.02 0.10 ± 0.00
DAS-77 400 2.66 ± 0.09 0.71 ± 0.03 0.88 ± 0.04 0.33 ± 0.02 1.99 ± 0.08 0.31 ± 0.02 0.42 ± 0.02 0.74 ± 0.08 0.14 ± 0.02**
DAS-77 2000 2.41 ± 0.1* 0.65 ± 0.06 0.78 ± 0.07 0.35 ± 0.02 1.91 ± 0.13 0.30 ± 0.02 0.32 ± 0.03 0.73 ± 0.01 0.14 ± 0.01*
  1. Values are mean ± S.E.M (n = 10). * p < 0.05, ** p < 0.01 vs. distilled water (One-way ANOVA followed by Dunnett’s posttest).
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BMC Complementary Medicine and Therapies

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